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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
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BAY 80-6946 (Copanlisib CAS number 1032568-63-0) is a small molecule inhibitor targeting class I phosphatidylinositol-3-kinase (PI3K) with potent inhibitory activity against PI3K- and PI3K- isoforms By blocking PI3K enzymatic activity Copanlisib interferes with downstream signaling pathways crucial for cell proliferation and survival In vitro studies demonstrate notable antiproliferative effects in cancer cell lines such as HuCCT-1 and EGI-1 (KRASG12D mutants) exhibiting IC50 values of approximately 147 nM and 137 nM respectively Clinical trials indicate potential utility in treating B-cell malignancies like chronic lymphocytic leukemia and non-Hodgkin lymphoma
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6A-azido-6A-deoxy-β-cyclodextrin is an azide-functionalized β-cyclodextrin derivative used as a reagent for click chemistry and bioconjugation. It contains a single azido substituent at the 6A position, is water-soluble, and enables efficient labeling and conjugation under aqueous conditions.
Enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation.
Single azido handle for site-selective modification.
Water-soluble scaffold compatible with aqueous reactions.
Applicable to host-guest chemistry and carrier modification.
Supplied with high reported chemical purity for reproducible results.
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Glycerol is odourless colorless viscous in nature and exists as a sweet tasting liquid. It can be derived naturally as well as from petrochemical feedstock. Glycerol has a wide variety of applications and is one of the most valuable and versatile chemical substances in nature. It can be used as an emollient solvent sweetening agent in pharmaceutical formulations cosmetics foodstuffs and toiletries. It is very stable and can be easily stored under normal temperature also it is non-irritating and has no adverse impact to the environment.
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